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Assay Report Card

Basic Information

ID: ALA4395492

Type: Binding

Description: Inhibition of GCase in human SH-SY5Y cells at 1 nM to 1 mM using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs in presence of conduritol B epoxide by fluorescence based assay relative to control

Organism: Homo sapiens

Cell type: SH-SY5Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
219.28-1.45-1.45
219.28-1.45-1.45
289.420.500.50
289.420.500.50
397.561.151.15
333.470.510.51
375.551.681.68
219.28-1.45-1.45
397.561.151.15
333.470.510.51
333.470.510.51
375.551.681.68
289.420.500.50
397.561.151.15
375.551.681.68