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ID: ALA4395492
Type: Binding
Description: Inhibition of GCase in human SH-SY5Y cells at 1 nM to 1 mM using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs in presence of conduritol B epoxide by fluorescence based assay relative to control
Organism: Homo sapiens
Cell type: SH-SY5Y
Bioactivity
Activity Types for Assay ALA4395492
Imax
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
219.28 | -1.45 | -1.45 |
219.28 | -1.45 | -1.45 |
289.42 | 0.50 | 0.50 |
289.42 | 0.50 | 0.50 |
397.56 | 1.15 | 1.15 |
333.47 | 0.51 | 0.51 |
375.55 | 1.68 | 1.68 |
219.28 | -1.45 | -1.45 |
397.56 | 1.15 | 1.15 |
333.47 | 0.51 | 0.51 |
333.47 | 0.51 | 0.51 |
375.55 | 1.68 | 1.68 |
289.42 | 0.50 | 0.50 |
397.56 | 1.15 | 1.15 |
375.55 | 1.68 | 1.68 |