Basic Information
ID: ALA4395511
Type: Binding
Description: Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as remaining enzyme activity at 50 uM using dGTP as substrate incubated for 15 mins by malachite green dye based pyrophosphatase coupled colorimetric assay
Format: BAO_0000219
Organism: Homo sapiens
Target: 7,8-dihydro-8-oxoguanine triphosphatase(ALA3708265)
Document: ALA4393699
Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as remaining enzyme activity at 50 uM using dGTP as substrate incubated for 15 mins by malachite green dye based pyrophosphatase coupled colorimetric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395511
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.41 | 3.88 | 3.88 |
| 287.43 | 3.41 | 3.41 |
| 231.28 | 2.18 | 2.18 |
| 237.26 | 2.33 | 2.33 |
| 224.26 | 3.24 | 3.24 |
| 255.25 | 2.47 | 2.47 |
| 229.28 | 1.73 | 1.73 |
| 213.22 | 2.76 | 2.76 |
| 300.39 | 2.52 | 2.52 |