Basic Information
ID: ALA4395644
Type: Binding
Description: Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as template primer incubated for 1 hr followed by the addition of (DIG)-dUTP and biotin-labeled dNTPs by ELISA
Format: BAO_0000357
Organism: Human immunodeficiency virus 1
Strain: 3B
Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)
Document: ALA4393704
Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as template primer incubated for 1 hr followed by the addition of (DIG)-dUTP and biotin-labeled dNTPs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395644
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 2.65 | 2.65 |
| 315.68 | 4.07 | 4.07 |
| 468.70 | 5.98 | 5.98 |
| 414.82 | 5.09 | 5.09 |
| 458.70 | 6.52 | 6.52 |
| 419.83 | 5.22 | 5.22 |
| 457.81 | 6.23 | 6.23 |