Basic Information
ID: ALA4395841
Type: Binding
Description: Competitive inhibition of human recombinant full length GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 mins followed by substrate and 25 uM ATP addition measured after 60 mins by ADP-Glo luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4395841
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.22 | 4.05 | 4.05 |
| 382.46 | 4.36 | 4.36 |
| 342.40 | 3.96 | 3.96 |
| 382.46 | 4.74 | 4.74 |
| 416.91 | 4.96 | 4.96 |
| 472.59 | 6.70 | 6.70 |
| 398.46 | 4.12 | 4.12 |
| 444.54 | 5.74 | 5.74 |
| 416.91 | 4.96 | 4.96 |
| 354.45 | 4.82 | 4.82 |
| 382.46 | 4.36 | 4.36 |
| 398.46 | 3.75 | 3.75 |
| 512.59 | 6.89 | 6.89 |
| 598.70 | 7.17 | 7.17 |
| 436.43 | 5.28 | 5.28 |
| 336.37 | 3.93 | 3.93 |
| 322.34 | 3.63 | 3.63 |
| 396.45 | 3.92 | 3.92 |
| 426.50 | 5.41 | 5.41 |
| 368.44 | 4.35 | 4.35 |
| 405.46 | 4.65 | 4.65 |
| 412.47 | 5.22 | 5.22 |
| 388.40 | 4.89 | 4.89 |
| 508.58 | 5.21 | 5.21 |
| 500.52 | 6.59 | 6.59 |
| 522.60 | 5.60 | 5.60 |
| 350.40 | 4.19 | 4.19 |
| 444.54 | 5.92 | 5.92 |
| 462.55 | 5.58 | 5.58 |
| 394.43 | 4.85 | 4.85 |
| 486.49 | 6.20 | 6.20 |
| 382.46 | 4.74 | 4.74 |
| 425.49 | 3.56 | 3.56 |
| 398.44 | 5.29 | 5.29 |
| 410.47 | 4.31 | 4.31 |
| 396.49 | 5.13 | 5.13 |
| 242.28 | 2.13 | 2.13 |
| 384.44 | 3.36 | 3.36 |
| 418.50 | 5.53 | 5.53 |
| 462.55 | 5.58 | 5.58 |