Basic Information
ID: ALA4395918
Type: Binding
Description: Inhibition of human topoisomerase 2alpha using supercoiled pNO1 plasmid as substrate after 30 mins by HTS assay
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4393709
Inhibition of human topoisomerase 2alpha using supercoiled pNO1 plasmid as substrate after 30 mins by HTS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395918
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 359.45 | 3.89 | 3.89 |
| 375.91 | 4.40 | 4.40 |
| 375.91 | 4.40 | 4.40 |
| 405.93 | 3.90 | 3.90 |
| 418.93 | 3.50 | 3.50 |
| 419.92 | 4.10 | 4.10 |
| 417.90 | 3.94 | 3.94 |
| 417.99 | 5.53 | 5.53 |
| 405.93 | 3.90 | 3.90 |
| 417.99 | 5.53 | 5.53 |
| 413.42 | 4.31 | 4.31 |
| 411.89 | 4.68 | 4.68 |
| 417.90 | 3.94 | 3.94 |
| 443.90 | 5.42 | 5.42 |
| 435.96 | 4.42 | 4.42 |
| 461.89 | 5.56 | 5.56 |
| 445.44 | 5.05 | 5.05 |
| 402.48 | 2.99 | 2.99 |
| 391.91 | 4.11 | 4.11 |
| 395.43 | 4.17 | 4.17 |
| 443.90 | 5.42 | 5.42 |
| 418.93 | 3.50 | 3.50 |
| 429.88 | 4.82 | 4.82 |
| 447.97 | 4.59 | 4.59 |
| 419.50 | 3.91 | 3.91 |
| 429.88 | 4.82 | 4.82 |
| 447.97 | 4.59 | 4.59 |
| 419.92 | 4.10 | 4.10 |
| 403.46 | 3.59 | 3.59 |
| 427.45 | 4.91 | 4.91 |
| 375.45 | 3.59 | 3.59 |
| 401.45 | 3.42 | 3.42 |
| 431.51 | 4.08 | 4.08 |
| 435.96 | 4.42 | 4.42 |
| 401.53 | 5.01 | 5.01 |
| 461.89 | 5.56 | 5.56 |
| 411.89 | 4.68 | 4.68 |
| 391.90 | 4.11 | 4.11 |
| 389.48 | 3.38 | 3.38 |