Basic Information
ID: ALA4395921
Type: Binding
Description: Inhibition of human topoisomerase-2alpha mediated decatenation at 125 uM using kinetoplast DNA as substrate after 30 mins in presence of ATP by ethidium bromide staining-based gel electrophoresis method relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4393709
Inhibition of human topoisomerase-2alpha mediated decatenation at 125 uM using kinetoplast DNA as substrate after 30 mins in presence of ATP by ethidium bromide staining-based gel electrophoresis method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395921
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.56 | 1.34 | 1.34 |
| 461.89 | 5.56 | 5.56 |
| 445.44 | 5.05 | 5.05 |
| 427.45 | 4.91 | 4.91 |