Basic Information
ID: ALA4395932
Type: Binding
Description: Inhibition of etoposide induced poison activity at human topoisomerase-2alpha assessed as linear DNA formation at 31.5 uM using supercoiled pBR322 DNA as substrate after 60 mins by ethidium bromide staining based agarose gel electrophoresis method (Rvb = 35.56 microM/min)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4395932
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.89 | 5.56 | 5.56 |
| 445.44 | 5.05 | 5.05 |
| 427.45 | 4.91 | 4.91 |