Basic Information
ID: ALA4395936
Type: Binding
Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 10 uM using linear pBR322 DNA as substrate measured up to 30 mins in presence of 2 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 2.810 microM/min)
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4393709
Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 10 uM using linear pBR322 DNA as substrate measured up to 30 mins in presence of 2 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 2.810 microM/min): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395936
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.45 | 4.91 | 4.91 |