Assay Report Card

Basic Information

ID: ALA4395937

Type: Binding

Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 10 uM using linear pBR322 DNA as substrate measured up to 30 mins in presence of 1 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 2.488 to 2.810 microM/min)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
427.454.914.91