Assay Report Card

Basic Information

ID: ALA4395961

Type: Binding

Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 40 uM using pBR322 as substrate measured up to 30 mins in presence of 0.05 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 0.238 to 0.559 microM/min)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
427.454.914.91