Assay Report Card

Basic Information

ID: ALA4395967

Type: Binding

Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 50 uM using pBR322 as substrate measured up to 30 mins in presence of 0.25 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 1.524 to 1.845 microM/min)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
427.454.914.91