Basic Information
ID: ALA4395969
Type: Binding
Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 50 uM using pBR322 as substrate measured up to 30 mins in presence of 0.075 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 0.559 microM/min)
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4393709
Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 50 uM using pBR322 as substrate measured up to 30 mins in presence of 0.075 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 0.559 microM/min): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395969
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.45 | 4.91 | 4.91 |