Assay Report Card

Basic Information

ID: ALA4396007

Type: Binding

Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 40 uM using linear pBR322 DNA as substrate measured up to 30 mins in presence of 0.5 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 2.858 to 2.876 microM/min)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
461.895.565.56