Basic Information
ID: ALA4396021
Type: Binding
Description: Inhibition of human topoisomerase-2alpha assessed as rate of ATP hydrolysis at 50 uM using linear pBR322 DNA as substrate measured up to 30 mins in presence of 0.025 mM ATP by pyruvate kinase/lactate dehydrogenase enzyme coupled assay (Rvb = 0.161 to 0.188 microM/min)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4396021
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.89 | 5.56 | 5.56 |