Basic Information
ID: ALA4396413
Type: Functional
Description: Antiinflammatory activity in human HepG2 cells assessed as inhibition of TNFalpha-induced IkappaBalpha degradation at 2 uM pretreated for 1 hr followed by TNFalpha addition and measured after 30 mins by Western blot analysis
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4396413
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.65 | 6.79 | 6.79 |
| 494.72 | 7.34 | 7.34 |
| 450.62 | 6.70 | 6.70 |
| 452.64 | 6.64 | 6.64 |
| 478.67 | 7.18 | 7.18 |
| 463.66 | 6.36 | 6.36 |
| 492.70 | 7.56 | 7.56 |
| 477.69 | 6.75 | 6.75 |
| 491.72 | 7.14 | 7.14 |
| 466.62 | 6.28 | 6.28 |
| 517.71 | 7.56 | 7.56 |
| 480.69 | 7.04 | 7.04 |
| 528.68 | 7.51 | 7.51 |
| 466.66 | 7.20 | 7.20 |
| 492.70 | 7.26 | 7.26 |
| 452.61 | 7.11 | 7.11 |
| 560.67 | 7.63 | 7.63 |
| 466.66 | 6.95 | 6.95 |
| 511.66 | 6.46 | 6.46 |
| 478.67 | 6.87 | 6.87 |
| 508.70 | 7.16 | 7.16 |
| 481.68 | 6.14 | 6.14 |
| 466.66 | 6.95 | 6.95 |
| 480.69 | 7.25 | 7.25 |
| 480.69 | 7.04 | 7.04 |