Basic Information
ID: ALA4396636
Type: Binding
Description: Inhibition of NorA efflux pump in multidrug resistant Staphylococcus aureus 1199B mutant assessed as norfloxacin MIC measured after 24 hrs by broth microdilution method (Rvb = 256 +/- 1 microg/ml)
Format: BAO_0000357
Organism: Staphylococcus aureus
Strain: 1199B
Target: Quinolone resistance protein norA(ALA5114)
Document: ALA4393730
Inhibition of NorA efflux pump in multidrug resistant Staphylococcus aureus 1199B mutant assessed as norfloxacin MIC measured after 24 hrs by broth microdilution method (Rvb = 256 +/- 1 microg/ml): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4396636
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.29 | 4.94 | 4.94 |
| 422.74 | 5.68 | 5.68 |
| 464.39 | 6.69 | 6.69 |
| 467.19 | 5.79 | 5.79 |
| 406.28 | 5.17 | 5.17 |
| 388.29 | 5.03 | 5.03 |