Inhibition of NorA efflux pump in multidrug resistant Staphylococcus aureus 1199B mutant assessed as reduction in norfloxacin MIC measured after 24 hr...

Basic Information

ID: ALA4396640

Type: Binding

Description: Inhibition of NorA efflux pump in multidrug resistant Staphylococcus aureus 1199B mutant assessed as reduction in norfloxacin MIC measured after 24 hrs by broth microdilution method relative to norfloxacin

Format: BAO_0000357

Organism: Staphylococcus aureus

Strain: 1199B

Target:  Quinolone resistance protein norA(ALA5114)

Document:  ALA4393730

Inhibition of NorA efflux pump in multidrug resistant Staphylococcus aureus 1199B mutant assessed as reduction in norfloxacin MIC measured after 24 hrs by broth microdilution method relative to norfloxacin: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
422.745.685.68
467.195.795.79
388.295.035.03