Inhibition of human recombinant JAK1 assessed as phosphorylation of substrate at 10 uM using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 ...

Basic Information

ID: ALA4396764

Type: Binding

Description: Inhibition of human recombinant JAK1 assessed as phosphorylation of substrate at 10 uM using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins in the presence of ATP by LANCE assay relative to control

Format: BAO_0000357

Organism: Homo sapiens

Target: Tyrosine-protein kinase JAK1(ALA2835)

Document: ALA4393739

Inhibition of human recombinant JAK1 assessed as phosphorylation of substrate at 10 uM using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins in the presence of ATP by LANCE assay relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4396764

Inhibition

Total(26)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
371.43	1.10	1.10
433.50	2.72	2.72
437.50	1.78	1.78
422.51	3.16	3.16
381.48	2.33	2.33
393.50	2.47	2.47
360.44	1.81	1.81
438.54	0.59	0.59
353.43	1.55	1.55
372.45	1.95	1.95
453.48	2.76	2.76
453.48	2.76	2.76
408.51	1.23	1.23
408.49	2.85	2.85
453.48	2.76	2.76
444.47	3.13	3.13
438.51	2.86	2.86
487.38	3.61	3.61
442.93	3.50	3.50
422.51	3.16	3.16
395.47	1.32	1.32
487.38	3.61	3.61
407.52	2.72	2.72
346.42	1.42	1.42
379.47	2.08	2.08
426.48	2.99	2.99