Basic Information
ID: ALA4396778
Type: Binding
Description: Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addition and measured after 1 hr by spectrofluorimetry
Format: BAO_0000357
Organism: Homo sapiens
Target: Proteasome Macropain subunit MB1(ALA4662)
Document: ALA4393740
Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addition and measured after 1 hr by spectrofluorimetry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4396778
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 719.92 | 2.58 | 2.58 |
| 689.81 | 2.20 | 2.20 |
| 653.82 | 3.27 | 3.27 |
| 685.82 | 3.23 | 3.23 |
| 727.90 | 4.40 | 4.40 |
| 641.77 | 1.88 | 1.88 |
| 726.88 | 3.95 | 3.95 |
| 767.97 | 3.17 | 3.17 |
| 694.86 | 2.93 | 2.93 |
| 691.87 | 1.95 | 1.95 |
| 597.71 | 1.86 | 1.86 |
| 691.86 | 2.42 | 2.42 |
| 726.94 | 2.04 | 2.04 |
| 643.81 | 1.31 | 1.31 |
| 758.77 | 4.94 | 4.94 |
| 727.90 | 4.40 | 4.40 |
| 753.94 | 2.78 | 2.78 |
| 742.90 | 3.51 | 3.51 |
| 585.66 | 0.46 | 0.46 |
| 736.87 | 3.45 | 3.45 |
| 685.91 | 2.53 | 2.53 |
| 657.85 | 1.75 | 1.75 |
| 712.91 | 1.65 | 1.65 |
| 637.78 | 2.64 | 2.64 |
| 688.83 | 2.87 | 2.87 |
| 629.80 | 0.97 | 0.97 |
| 719.92 | 2.73 | 2.73 |
| 761.99 | 3.41 | 3.41 |
| 711.93 | 2.25 | 2.25 |
| 776.01 | 3.80 | 3.80 |
| 673.81 | 3.23 | 3.23 |
| 689.81 | 2.46 | 2.46 |