Basic Information
ID: ALA4396801
Type: Binding
Description: Potency index, ratio of JO146 IC50 to compound IC50 for inhibition of recombinant chlamydia trachomatis serovar L2 434/Bu/ATCC VR-902B HtrA expressed in Escherichia coli BL21(DE3) using MeOCoum-ENLHLPLPIIF-NH-DNP as fluorescent mimotope preincubated for 20 mins followed by mimotope addition in presence of fluorophore 7-methoxycoumarin-4-acetic acid by plate reader based fluorescence assay
Format: BAO_0000019
Organism: Chlamydia trachomatis 434/Bu
Strain: ATCC VR-902B
Target: Unchecked(ALA612545)
Document: ALA4393742
Potency index, ratio of JO146 IC50 to compound IC50 for inhibition of recombinant chlamydia trachomatis serovar L2 434/Bu/ATCC VR-902B HtrA expressed in Escherichia coli BL21(DE3) using MeOCoum-ENLHLPLPIIF-NH-DNP as fluorescent mimotope preincubated for 20 mins followed by mimotope addition in presence of fluorophore 7-methoxycoumarin-4-acetic acid by plate reader based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4396801
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 601.68 | 6.12 | 6.12 |
| 453.58 | 2.22 | 2.22 |
| 399.53 | 1.66 | 1.66 |
| 480.63 | 3.01 | 3.01 |
| 629.74 | 6.76 | 6.76 |
| 558.75 | 4.94 | 4.94 |
| 530.69 | 4.16 | 4.16 |
| 615.71 | 6.37 | 6.37 |
| 465.59 | 2.22 | 2.22 |
| 440.54 | 0.72 | 0.72 |
| 454.61 | 2.15 | 2.15 |
| 615.71 | 6.37 | 6.37 |
| 615.71 | 6.37 | 6.37 |
| 466.62 | 2.29 | 2.29 |
| 439.55 | 1.83 | 1.83 |
| 466.62 | 2.31 | 2.31 |
| 615.71 | 6.37 | 6.37 |
| 480.63 | 3.15 | 3.15 |
| 440.59 | 1.76 | 1.76 |