Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubated...

Basic Information

ID: ALA4397057

Type: Binding

Description: Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubated for 15 mins followed by substrate addition and measured after 45 mins by AAO/horse radish peroxidase enzyme coupled assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Methionine aminopeptidase 2(ALA3922)

Document: ALA4396866

Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubated for 15 mins followed by substrate addition and measured after 45 mins by AAO/horse radish peroxidase enzyme coupled assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4397057

IC50

Total(35)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
330.41	1.57	1.57
314.34	1.11	1.11
316.40	1.85	1.85
286.69	0.35	0.35
316.38	1.53	1.53
405.81	1.36	1.36
379.24	2.78	2.78
344.44	1.88	1.88
419.84	2.22	2.22
310.35	1.47	1.47
376.81	2.57	2.57
419.84	2.22	2.22
330.41	1.84	1.84
387.80	2.13	2.13
431.85	2.15	2.15
417.82	1.76	1.76
387.80	2.13	2.13
405.81	1.36	1.36
330.41	1.84	1.84
300.72	0.69	0.69
376.81	2.57	2.57
344.80	2.12	2.12
362.79	2.26	2.26
328.34	1.61	1.61
344.80	2.12	2.12
346.33	1.75	1.75
387.80	2.13	2.13
330.41	1.84	1.84
330.41	1.57	1.57
314.41	2.46	2.46
330.41	1.57	1.57
376.81	2.57	2.57
328.34	1.61	1.61
324.38	1.78	1.78
344.80	2.12	2.12