Basic Information
ID: ALA4397057
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubated for 15 mins followed by substrate addition and measured after 45 mins by AAO/horse radish peroxidase enzyme coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4397057
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.41 | 1.57 | 1.57 |
| 314.34 | 1.11 | 1.11 |
| 316.40 | 1.85 | 1.85 |
| 286.69 | 0.35 | 0.35 |
| 316.38 | 1.53 | 1.53 |
| 405.81 | 1.36 | 1.36 |
| 379.24 | 2.78 | 2.78 |
| 344.44 | 1.88 | 1.88 |
| 419.84 | 2.22 | 2.22 |
| 310.35 | 1.47 | 1.47 |
| 376.81 | 2.57 | 2.57 |
| 419.84 | 2.22 | 2.22 |
| 330.41 | 1.84 | 1.84 |
| 387.80 | 2.13 | 2.13 |
| 431.85 | 2.15 | 2.15 |
| 417.82 | 1.76 | 1.76 |
| 387.80 | 2.13 | 2.13 |
| 405.81 | 1.36 | 1.36 |
| 330.41 | 1.84 | 1.84 |
| 300.72 | 0.69 | 0.69 |
| 376.81 | 2.57 | 2.57 |
| 344.80 | 2.12 | 2.12 |
| 362.79 | 2.26 | 2.26 |
| 328.34 | 1.61 | 1.61 |
| 344.80 | 2.12 | 2.12 |
| 346.33 | 1.75 | 1.75 |
| 387.80 | 2.13 | 2.13 |
| 330.41 | 1.84 | 1.84 |
| 330.41 | 1.57 | 1.57 |
| 314.41 | 2.46 | 2.46 |
| 330.41 | 1.57 | 1.57 |
| 376.81 | 2.57 | 2.57 |
| 328.34 | 1.61 | 1.61 |
| 324.38 | 1.78 | 1.78 |
| 344.80 | 2.12 | 2.12 |