Assay Report Card

Basic Information

ID: ALA4397135

Type: Toxicity

Description: Selectivity ratio of EC50 for activation of non-specific gene expression in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as CMV driven gene expression to EC50 for activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as LTR-driven gene expression

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
349.433.333.33
540.711.431.43
364.784.614.61
310.813.903.90
311.793.303.30
345.254.564.56
378.804.924.92
341.233.703.70
324.834.214.21
321.793.473.47
311.793.303.30
345.254.564.56
344.364.274.27