Basic Information
ID: ALA4397429
Type: Binding
Description: Inhibition of N-terminal GST-tagged human PDE5A1 expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate measured after 30 mins by scintillation proximity assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4397429
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.41 | 2.21 | 2.21 |
| 474.59 | 1.61 | 1.61 |
| 448.59 | 2.29 | 2.29 |
| 455.56 | 2.06 | 2.06 |
| 437.52 | 2.10 | 2.10 |
| 372.43 | 1.77 | 1.77 |
| 440.54 | 3.30 | 3.30 |
| 344.42 | 2.84 | 2.84 |
| 441.58 | 2.54 | 2.54 |
| 428.53 | 3.21 | 3.21 |
| 522.67 | 1.67 | 1.67 |
| 426.56 | 3.63 | 3.63 |
| 379.48 | 2.72 | 2.72 |
| 301.39 | 2.93 | 2.93 |
| 463.56 | 2.59 | 2.59 |
| 357.45 | 3.70 | 3.70 |
| 426.56 | 3.77 | 3.77 |
| 398.51 | 3.98 | 3.98 |