Assay Report Card

Basic Information

ID: ALA4397499

Type: Functional

Description: Anti-hypersensitive activity in MCT-induced pulmonary arterial hypertension Sprague-Dawley rat model assessed as reduction in mean pulmonary artery pressure at 100 mg/kg administered once daily for 21 days starting from 21 days post-MCT challenge by right cardiac catheter method

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
551.634.204.20
474.591.611.61
441.582.542.54