Basic Information
ID: ALA4397636
Type: ADME
Description: Half-life in ICR/CD-1 mouse liver S9 fraction at 2 uM incubated for 5 mins under shaking condition in presence of NADPH regenerating system by LC-MS/MS analysis
Format: BAO_0000220
Organism: Mus musculus
Strain: ICR/CD-1
Tissue: Liver
Subcellular Fraction: S9
Target: ADMET(ALA612558)
Document: ALA4396877
Half-life in ICR/CD-1 mouse liver S9 fraction at 2 uM incubated for 5 mins under shaking condition in presence of NADPH regenerating system by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4397636
t1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.47 | 3.59 | 3.59 |
| 336.50 | 2.88 | 2.88 |
| 433.02 | 4.89 | 4.89 |
| 337.49 | 2.15 | 2.15 |
| 380.51 | 2.36 | 2.36 |
| 357.91 | 2.62 | 2.62 |
| 398.57 | 4.24 | 4.24 |
| 367.47 | 2.48 | 2.48 |
| 391.36 | 3.88 | 3.88 |
| 428.60 | 4.15 | 4.15 |
| 323.46 | 1.97 | 1.97 |
| 428.60 | 4.25 | 4.25 |
| 406.47 | 3.47 | 3.47 |
| 357.91 | 2.62 | 2.62 |
| 416.56 | 4.38 | 4.38 |
| 402.36 | 2.73 | 2.73 |
| 412.60 | 4.55 | 4.55 |
| 356.92 | 3.23 | 3.23 |
| 394.58 | 3.75 | 3.75 |
| 404.00 | 3.56 | 3.56 |
| 405.39 | 4.19 | 4.19 |
| 428.60 | 4.25 | 4.25 |
| 428.60 | 4.25 | 4.25 |
| 401.37 | 3.33 | 3.33 |
| 366.48 | 2.30 | 2.30 |
| 429.59 | 3.68 | 3.68 |
| 326.47 | 1.31 | 1.31 |
| 424.92 | 4.24 | 4.24 |
| 408.61 | 4.01 | 4.01 |
| 350.53 | 3.13 | 3.13 |
| 358.45 | 2.85 | 2.85 |
| 435.47 | 3.50 | 3.50 |
| 426.63 | 4.86 | 4.86 |
| 485.37 | 4.23 | 4.23 |
| 341.48 | 2.18 | 2.18 |
| 322.47 | 2.57 | 2.57 |
| 378.58 | 3.87 | 3.87 |
| 356.92 | 3.23 | 3.23 |
| 377.96 | 2.99 | 2.99 |
| 388.48 | 3.17 | 3.17 |
| 431.40 | 3.34 | 3.34 |
| 390.47 | 3.59 | 3.59 |
| 336.50 | 2.88 | 2.88 |
| 434.65 | 4.21 | 4.21 |
| 352.50 | 2.58 | 2.58 |
| 405.39 | 4.19 | 4.19 |
| 398.57 | 4.24 | 4.24 |
| 391.36 | 3.88 | 3.88 |
| 326.47 | 1.31 | 1.31 |
| 366.53 | 2.89 | 2.89 |
| 398.57 | 4.24 | 4.24 |
| 428.60 | 4.25 | 4.25 |
| 429.42 | 3.90 | 3.90 |
| 412.60 | 4.55 | 4.55 |
| 350.53 | 3.19 | 3.19 |
| 416.56 | 4.38 | 4.38 |
| 382.53 | 2.59 | 2.59 |
| 341.45 | 2.11 | 2.11 |
| 364.56 | 3.70 | 3.70 |
| 337.49 | 2.15 | 2.15 |
| 428.60 | 4.25 | 4.25 |
| 363.94 | 2.68 | 2.68 |
| 391.36 | 3.88 | 3.88 |
| 448.63 | 5.39 | 5.39 |
| 364.56 | 3.50 | 3.50 |
| 367.47 | 2.48 | 2.48 |
| 435.82 | 3.99 | 3.99 |
| 466.57 | 5.26 | 5.26 |
| 466.57 | 5.26 | 5.26 |
| 437.35 | 3.61 | 3.61 |
| 433.02 | 4.89 | 4.89 |
| 372.53 | 3.72 | 3.72 |
| 352.50 | 2.58 | 2.58 |
| 384.50 | -0.03 | -0.03 |
| 433.02 | 4.89 | 4.89 |
| 373.52 | 3.12 | 3.12 |
| 382.53 | 2.59 | 2.59 |
| 401.37 | 3.33 | 3.33 |
| 443.41 | 3.27 | 3.27 |
| 361.51 | 2.75 | 2.75 |
| 401.37 | 3.33 | 3.33 |
| 366.48 | 2.30 | 2.30 |
| 347.48 | 2.44 | 2.44 |
| 380.55 | 3.36 | 3.36 |
| 416.56 | 4.38 | 4.38 |
| 406.98 | 4.38 | 4.38 |