Basic Information
ID: ALA4397815
Type: Binding
Description: Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclast differentiation by measuring decrease in multinucleated TRAP+ cells at 5 uM supplemented with fresh medium containing compounds every 2 days for 5 to 6 days by TRAP staining-based microscopic analysis relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4397815
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.53 | 5.26 | 5.26 |