Basic Information
ID: ALA4397817
Type: Binding
Description: Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in TRAP activity at 5 uM measured after 3 days by colorimetric assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4397817
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.53 | 5.26 | 5.26 |
| 479.50 | 5.49 | 5.49 |
| 457.55 | 5.22 | 5.22 |
| 411.55 | 5.17 | 5.17 |
| 431.58 | 5.42 | 5.42 |
| 469.59 | 5.09 | 5.09 |
| 445.59 | 5.15 | 5.15 |
| 429.50 | 4.61 | 4.61 |
| 453.63 | 6.34 | 6.34 |
| 457.55 | 5.22 | 5.22 |
| 425.58 | 5.56 | 5.56 |
| 469.59 | 5.09 | 5.09 |
| 441.53 | 4.48 | 4.48 |
| 440.55 | 4.48 | 4.48 |
| 474.00 | 5.74 | 5.74 |
| 440.55 | 4.48 | 4.48 |
| 445.59 | 5.15 | 5.15 |
| 446.58 | 4.54 | 4.54 |
| 429.50 | 4.61 | 4.61 |
| 453.59 | 5.47 | 5.47 |
| 403.53 | 4.64 | 4.64 |
| 454.57 | 4.53 | 4.53 |
| 467.61 | 5.86 | 5.86 |
| 425.53 | 4.78 | 4.78 |
| 469.59 | 5.09 | 5.09 |
| 425.58 | 5.56 | 5.56 |
| 411.51 | 4.47 | 4.47 |
| 457.55 | 5.22 | 5.22 |
| 425.53 | 4.78 | 4.78 |
| 425.53 | 4.69 | 4.69 |
| 474.00 | 5.74 | 5.74 |
| 489.60 | 3.87 | 3.87 |
| 439.56 | 5.08 | 5.08 |
| 496.61 | 4.30 | 4.30 |
| 457.55 | 5.22 | 5.22 |
| 439.60 | 5.95 | 5.95 |
| 445.61 | 5.81 | 5.81 |