Basic Information
ID: ALA4397826
Type: Binding
Description: Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclast differentiation by measuring decrease in nuclei number of F-actin ring formation at 5 uM supplemented with fresh medium containing compounds every 2 days for 5 to 6 days by rhodamine phalloidin/DAPI staining-based microscopic analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4397826
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.55 | 5.22 | 5.22 |
| 425.58 | 5.56 | 5.56 |
| 474.00 | 5.74 | 5.74 |
| 439.56 | 5.08 | 5.08 |