Basic Information
ID: ALA4397904
Type: Binding
Description: Inhibition of PDE4 in human PBMC assessed as reduction in LPS-stimulated TNFalpha production at 10 uM preincubated for 1 hr followed by LPS stimulation and measured after 18 to 20 hrs by ELISA relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4397904
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.58 | 5.14 | 5.14 |
| 394.52 | 4.36 | 4.36 |