Basic Information
ID: ALA4397963
Type: Binding
Description: Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed by substrate addition and and measured after 30 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4397963
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.30 | 2.48 | 2.48 |
| 390.42 | 3.38 | 3.38 |
| 404.42 | 4.62 | 4.62 |
| 362.50 | 5.43 | 5.43 |
| 364.47 | 4.82 | 4.82 |
| 362.50 | 5.38 | 5.38 |