Basic Information
ID: ALA4397964
Type: Binding
Description: Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4397964
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.30 | 2.48 | 2.48 |
| 390.42 | 3.38 | 3.38 |
| 404.42 | 4.62 | 4.62 |
| 362.50 | 5.43 | 5.43 |
| 364.47 | 4.82 | 4.82 |
| 362.50 | 5.38 | 5.38 |