In vivo inhibition of PRMT4 in nude BALB/c mouse xenografted with human MOLM13 cells assessed as reduction in asymmetric dimethyl arginine level at 10...

Basic Information

ID: ALA4398119

Type: Functional

Description: In vivo inhibition of PRMT4 in nude BALB/c mouse xenografted with human MOLM13 cells assessed as reduction in asymmetric dimethyl arginine level at 100 mg/kg, po administered daily for 18 days measured 6 hrs post-last dose by Western blot analysis

Format: BAO_0000218

Organism: Mus musculus

Strain: BALB/c

Target:  Mus musculus(ALA375)

Document:  ALA4396888

In vivo inhibition of PRMT4 in nude BALB/c mouse xenografted with human MOLM13 cells assessed as reduction in asymmetric dimethyl arginine level at 100 mg/kg, po administered daily for 18 days measured 6 hrs post-last dose by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
409.563.333.33