Basic Information
ID: ALA4398583
Type: Binding
Description: Binding affinity to N-terminal GST tagged recombinant human DCN1 (58 to 259 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in DCN1-FAM-labelled N-terminal acetylated UBE2M (1 to 21 residues) protein-protein interaction after 30 mins by HTRF assay
Format: BAO_0000019
Organism: Homo sapiens
Target: DCN1-like protein 1(ALA4105838)
Document: ALA4396897
Binding affinity to N-terminal GST tagged recombinant human DCN1 (58 to 259 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in DCN1-FAM-labelled N-terminal acetylated UBE2M (1 to 21 residues) protein-protein interaction after 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4398583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.53 | 4.52 | 4.52 |
| 500.50 | 5.53 | 5.53 |
| 433.48 | 2.52 | 2.52 |
| 516.61 | 6.52 | 6.52 |
| 456.99 | 3.09 | 3.09 |
| 484.63 | 4.99 | 4.99 |
| 491.43 | 3.75 | 3.75 |
| 444.34 | 3.18 | 3.18 |
| 400.94 | 5.00 | 5.00 |
| 407.53 | 3.54 | 3.54 |
| 442.57 | 3.32 | 3.32 |
| 455.53 | 2.44 | 2.44 |
| 471.59 | 4.08 | 4.08 |
| 434.53 | 4.45 | 4.45 |
| 445.39 | 5.11 | 5.11 |
| 456.99 | 3.09 | 3.09 |
| 404.97 | 5.78 | 5.78 |
| 404.48 | 2.90 | 2.90 |
| 424.53 | 3.76 | 3.76 |
| 399.89 | 3.07 | 3.07 |
| 490.57 | 2.55 | 2.55 |
| 371.48 | 2.48 | 2.48 |
| 400.94 | 5.00 | 5.00 |
| 470.60 | 4.68 | 4.68 |
| 534.10 | 6.21 | 6.21 |
| 434.34 | 3.72 | 3.72 |
| 436.57 | 2.75 | 2.75 |
| 457.56 | 3.77 | 3.77 |
| 438.47 | 2.03 | 2.03 |
| 585.82 | 3.76 | 3.76 |
| 425.51 | 2.18 | 2.18 |
| 395.47 | 2.42 | 2.42 |
| 399.89 | 3.07 | 3.07 |
| 456.57 | 4.37 | 4.37 |
| 506.63 | 5.53 | 5.53 |
| 450.55 | 4.31 | 4.31 |
| 402.96 | 5.55 | 5.55 |
| 435.39 | 5.66 | 5.66 |
| 512.62 | 2.47 | 2.47 |
| 440.51 | 3.04 | 3.04 |
| 354.42 | 1.74 | 1.74 |
| 379.47 | 2.72 | 2.72 |
| 426.50 | 2.60 | 2.60 |
| 472.58 | 3.35 | 3.35 |
| 365.45 | 2.42 | 2.42 |
| 470.60 | 4.56 | 4.56 |
| 355.47 | 3.68 | 3.68 |
| 367.48 | 3.74 | 3.74 |
| 380.52 | 4.66 | 4.66 |
| 453.55 | 3.65 | 3.65 |