Basic Information
ID: ALA4398700
Type: Binding
Description: Inhibition of bovine aortic smooth muscle PDE5 at 10 uM using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation counting method relative to control
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA4398700
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.28 | 1.50 | 1.50 |
| 331.81 | 5.69 | 5.69 |
| 327.39 | 5.05 | 5.05 |
| 313.71 | 4.29 | 4.29 |
| 313.71 | 4.29 | 4.29 |
| 293.29 | 3.68 | 3.68 |
| 341.41 | 4.92 | 4.92 |
| 309.29 | 3.64 | 3.64 |
| 335.33 | 4.21 | 4.21 |
| 275.74 | 3.28 | 3.28 |
| 303.38 | 2.36 | 2.36 |
| 318.30 | 4.77 | 4.77 |
| 325.42 | 4.95 | 4.95 |
| 309.29 | 3.90 | 3.90 |
| 409.41 | 5.94 | 5.94 |
| 406.45 | 5.39 | 5.39 |
| 355.44 | 4.96 | 4.96 |
| 266.30 | 2.50 | 2.50 |
| 423.87 | 6.44 | 6.44 |
| 359.86 | 5.60 | 5.60 |
| 265.32 | 3.25 | 3.25 |
| 310.18 | 3.93 | 3.93 |
| 321.30 | 4.20 | 4.20 |
| 255.71 | 4.03 | 4.03 |
| 323.31 | 3.69 | 3.69 |
| 411.43 | 5.72 | 5.72 |
| 361.83 | 5.70 | 5.70 |
| 327.73 | 4.33 | 4.33 |
| 309.29 | 3.64 | 3.64 |
| 319.38 | 2.03 | 2.03 |
| 309.29 | 3.64 | 3.64 |
| 397.40 | 5.67 | 5.67 |
| 309.29 | 3.64 | 3.64 |
| 366.25 | 6.35 | 6.35 |
| 323.27 | 3.36 | 3.36 |
| 286.29 | 2.53 | 2.53 |
| 416.45 | 5.26 | 5.26 |
| 309.29 | 3.64 | 3.64 |
| 323.31 | 3.69 | 3.69 |
| 348.45 | 4.24 | 4.24 |
| 323.31 | 3.69 | 3.69 |
| 284.31 | 1.72 | 1.72 |
| 339.31 | 3.65 | 3.65 |
| 389.42 | 5.79 | 5.79 |
| 313.71 | 4.29 | 4.29 |
| 379.81 | 6.57 | 6.57 |
| 171.12 | 2.58 | 2.58 |
| 407.41 | 5.93 | 5.93 |
| 297.36 | 5.04 | 5.04 |
| 403.45 | 6.18 | 6.18 |
| 355.40 | 4.64 | 4.64 |
| 343.73 | 4.30 | 4.30 |
| 327.73 | 4.33 | 4.33 |
| 375.86 | 5.57 | 5.57 |
| 279.26 | 3.64 | 3.64 |
| 345.83 | 5.56 | 5.56 |
| 330.82 | 6.30 | 6.30 |
| 331.81 | 5.69 | 5.69 |
| 341.38 | 4.62 | 4.62 |
| 362.40 | 4.63 | 4.63 |
| 281.75 | 4.54 | 4.54 |
| 253.31 | 3.18 | 3.18 |
| 310.18 | 3.93 | 3.93 |
| 359.86 | 5.60 | 5.60 |
| 336.31 | 3.42 | 3.42 |
| 363.47 | 3.00 | 3.00 |
| 338.84 | 5.02 | 5.02 |
| 321.42 | 4.77 | 4.77 |
| 327.73 | 4.33 | 4.33 |
| 241.29 | 2.63 | 2.63 |
| 351.37 | 4.81 | 4.81 |
| 364.45 | 3.21 | 3.21 |
| 367.76 | 4.92 | 4.92 |
| 309.29 | 3.64 | 3.64 |
| 355.87 | 5.43 | 5.43 |
| 323.31 | 3.99 | 3.99 |
| 311.39 | 4.91 | 4.91 |
| 295.26 | 3.34 | 3.34 |
| 398.39 | 5.06 | 5.06 |
| 341.41 | 4.92 | 4.92 |
| 341.41 | 4.92 | 4.92 |