Basic Information
ID: ALA4398796
Type: Binding
Description: Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged EGFR (668 to 1210 residues) T790M/L858R/C797S mutant expressed in baculovirus expression system using poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4398796
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.36 | 4.43 | 4.43 |
| 696.73 | 6.86 | 6.86 |
| 569.68 | 5.99 | 5.99 |
| 571.70 | 6.62 | 6.62 |
| 569.68 | 5.99 | 5.99 |
| 543.64 | 5.98 | 5.98 |
| 660.75 | 6.58 | 6.58 |
| 529.62 | 5.42 | 5.42 |
| 660.75 | 6.58 | 6.58 |
| 563.59 | 5.87 | 5.87 |
| 660.75 | 6.58 | 6.58 |
| 605.71 | 7.01 | 7.01 |
| 578.60 | 5.45 | 5.45 |
| 666.80 | 6.79 | 6.79 |
| 515.59 | 5.49 | 5.49 |
| 529.62 | 5.42 | 5.42 |
| 676.75 | 5.96 | 5.96 |
| 515.59 | 5.49 | 5.49 |
| 648.69 | 5.53 | 5.53 |
| 660.75 | 6.58 | 6.58 |