Assay Report Card

Basic Information

ID: ALA4398892

Type: Functional

Description: Antiviral activity against HBV genotype D hydrodynamically infected as pHBV1.3 mer plasmid carrying viral genome in C57BL/6 mouse assessed as log10 reduction in serum viral DNA level at 0.10 to 0.50 mmol/kg/day, po via gavage administered as twice daily dosage and measured on day 4 post treatment by qRT-PCR analysis

Organism: hepatitis B virus genotype D

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
635.523.043.04
582.000.970.97