Basic Information
ID: ALA4398996
Type: Binding
Description: Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assay
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA4398996
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 138.12 | 1.09 | 1.09 |
| 170.12 | 0.50 | 0.50 |
| 154.12 | 0.80 | 0.80 |
| 212.20 | 1.41 | 1.41 |
| 377.42 | 2.01 | 2.01 |
| 339.41 | 2.07 | 2.07 |
| 309.39 | 1.97 | 1.97 |
| 175.25 | 0.41 | 0.41 |
| 325.34 | 0.44 | 0.44 |
| 295.36 | 1.58 | 1.58 |
| 327.36 | 0.99 | 0.99 |
| 345.42 | 2.60 | 2.60 |
| 369.44 | 1.90 | 1.90 |
| 419.50 | 2.92 | 2.92 |
| 309.34 | 0.74 | 0.74 |
| 341.39 | 1.38 | 1.38 |
| 189.28 | 0.80 | 0.80 |
| 355.41 | 1.77 | 1.77 |
| 225.31 | 1.42 | 1.42 |
| 383.47 | 2.29 | 2.29 |
| 325.39 | 1.68 | 1.68 |
| 367.42 | 1.35 | 1.35 |
| 397.49 | 2.68 | 2.68 |
| 293.34 | 1.03 | 1.03 |
| 243.30 | 1.56 | 1.56 |
| 379.41 | 2.44 | 2.44 |
| 203.31 | 1.19 | 1.19 |
| 323.41 | 2.36 | 2.36 |
| 311.36 | 1.29 | 1.29 |
| 395.41 | 2.15 | 2.15 |
| 437.49 | 3.06 | 3.06 |
| 173.24 | -0.15 | -0.15 |
| 361.42 | 2.30 | 2.30 |
| 363.41 | 2.74 | 2.74 |