Basic Information
ID: ALA4399082
Type: Binding
Description: Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate at 100 uM preincubated for 10 mins followed by substrate addition and measured after 30 mins by spectrophotometric analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Insulin-degrading enzyme(ALA1293287)
Document: ALA4396912
Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate at 100 uM preincubated for 10 mins followed by substrate addition and measured after 30 mins by spectrophotometric analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4399082
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.37 | 3.52 | 3.52 |
| 359.45 | 2.99 | 2.99 |
| 383.38 | 2.88 | 2.88 |
| 345.42 | 2.90 | 2.90 |
| 346.41 | 2.29 | 2.29 |