Basic Information
ID: ALA4399410
Type: ADME
Description: Cytotoxicity against human HepG2 cells harbouring CYP2B6-hCAR gene assessed as reduction in cell viability at >10 uM incubated for 24 hrs by cell titer-Glo cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: HepG2(ALA395)
Document: ALA4396920
Cytotoxicity against human HepG2 cells harbouring CYP2B6-hCAR gene assessed as reduction in cell viability at >10 uM incubated for 24 hrs by cell titer-Glo cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4399410
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.75 | 6.57 | 6.57 |
| 452.37 | 7.07 | 7.07 |
| 436.30 | 6.61 | 6.61 |
| 458.41 | 7.22 | 7.22 |
| 401.85 | 5.95 | 5.95 |
| 470.30 | 6.94 | 6.94 |
| 416.33 | 6.23 | 6.23 |
| 484.45 | 7.97 | 7.97 |
| 452.37 | 7.07 | 7.07 |
| 512.51 | 8.27 | 8.27 |
| 401.85 | 5.95 | 5.95 |
| 402.31 | 5.92 | 5.92 |
| 432.33 | 5.93 | 5.93 |
| 436.75 | 6.57 | 6.57 |
| 444.39 | 7.04 | 7.04 |
| 457.36 | 5.99 | 5.99 |
| 423.52 | 6.60 | 6.60 |
| 478.40 | 7.59 | 7.59 |
| 481.20 | 6.68 | 6.68 |
| 420.30 | 6.06 | 6.06 |
| 397.43 | 5.31 | 5.31 |
| 354.26 | 4.82 | 4.82 |
| 393.45 | 5.27 | 5.27 |
| 427.32 | 5.79 | 5.79 |
| 459.51 | 7.09 | 7.09 |