Basic Information
ID: ALA4399412
Type: Binding
Description: Agonist activity at human PXR transfected in human HepG2 cells cotransfected with CYP3A4 incubated for 23 hrs by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Pregnane X receptor(ALA3401)
Document: ALA4396920
Agonist activity at human PXR transfected in human HepG2 cells cotransfected with CYP3A4 incubated for 23 hrs by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4399412
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.75 | 6.57 | 6.57 |
| 420.68 | 6.11 | 6.11 |
| 435.40 | 6.32 | 6.32 |
| 512.51 | 8.27 | 8.27 |
| 436.30 | 6.61 | 6.61 |
| 478.40 | 7.59 | 7.59 |
| 367.41 | 5.30 | 5.30 |
| 459.51 | 7.09 | 7.09 |