Basic Information
ID: ALA4399425
Type: Binding
Description: Inhibition of 20S proteosome beta 2 purified from human HCT116 cells using Boc-LRR-AMC as substrate incubated for 30 to 120 mins by fluorimetry
Format: BAO_0000019
Organism: Homo sapiens
Target: Proteasome Macropain subunit(ALA3492)
Document: ALA4396921
Inhibition of 20S proteosome beta 2 purified from human HCT116 cells using Boc-LRR-AMC as substrate incubated for 30 to 120 mins by fluorimetry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4399425
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.63 | 3.59 | 3.59 |
| 567.69 | 5.02 | 5.02 |
| 646.83 | 5.54 | 5.54 |
| 590.76 | 2.61 | 2.61 |
| 529.64 | 3.94 | 3.94 |
| 626.77 | 4.41 | 4.41 |
| 588.75 | 2.82 | 2.82 |
| 495.62 | 3.74 | 3.74 |
| 496.56 | 1.57 | 1.57 |
| 628.79 | 4.21 | 4.21 |
| 497.64 | 3.54 | 3.54 |
| 531.65 | 3.73 | 3.73 |
| 644.81 | 5.75 | 5.75 |
| 565.67 | 5.22 | 5.22 |
| 576.78 | 3.52 | 3.52 |
| 545.64 | 3.65 | 3.65 |
| 636.83 | 4.34 | 4.34 |
| 608.78 | 4.27 | 4.27 |
| 483.61 | 3.15 | 3.15 |
| 498.58 | 1.37 | 1.37 |
| 610.80 | 4.07 | 4.07 |
| 574.76 | 3.73 | 3.73 |
| 547.65 | 3.44 | 3.44 |
| 634.82 | 4.54 | 4.54 |
| 481.59 | 3.35 | 3.35 |