Potentiation of cisplatin-induced apoptosis in human Cal27CisR cells assessed as caspase-3/7 activity at 1 uM preincubated for 48 hrs followed by cisp...

Basic Information

ID: ALA4399712

Type: Functional

Description: Potentiation of cisplatin-induced apoptosis in human Cal27CisR cells assessed as caspase-3/7 activity at 1 uM preincubated for 48 hrs followed by cisplatin addition and further incubation for 24 hrs treated with 20 uM pan capsase inhibitor QVD for 30 mins prior to compound addition by CellEvent caspase 3/7 green detection reagent/Hoechst 33342 staining based arrayscan analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Unchecked(ALA612545)

Document:  ALA4396934

Potentiation of cisplatin-induced apoptosis in human Cal27CisR cells assessed as caspase-3/7 activity at 1 uM preincubated for 48 hrs followed by cisplatin addition and further incubation for 24 hrs treated with 20 uM pan capsase inhibitor QVD for 30 mins prior to compound addition by CellEvent caspase 3/7 green detection reagent/Hoechst 33342 staining based arrayscan analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
363.372.622.62
357.372.472.47