Basic Information
ID: ALA4399713
Type: Functional
Description: Potentiation of cisplatin-induced apoptosis in human CAL27 cells assessed as caspase-3/7 activity at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and further incubation for 24 hrs treated with 20 uM pan capsase inhibitor QVD for 30 mins prior to compound addition by CellEvent caspase 3/7 green detection reagent/Hoechst 33342 staining based arrayscan analysis
Organism: Homo sapiens
Cell type: CAL-27
Activity Charts
Bioactivity
Activity Types for Assay ALA4399713
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.37 | 2.62 | 2.62 |
| 357.37 | 2.47 | 2.47 |