Basic Information
ID: ALA4399730
Type: Binding
Description: Inhibition of C-terminal His-fusion tagged/N-terminal Strep-2 tagged recombinant human HDAC8 (1 to 377 residues) expressed in insect cells using Boc-Lys(TFa)-AMC as substrate preincubated for 5 mins followed by substrate addition and further incubation for 90 mins measured after 15 mins by microplate reader based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4399730
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 349.43 | 3.33 | 3.33 |
| 335.41 | 2.80 | 2.80 |
| 341.41 | 3.64 | 3.64 |
| 514.53 | 5.36 | 5.36 |
| 363.37 | 2.62 | 2.62 |
| 357.37 | 2.47 | 2.47 |