Basic Information
ID: ALA4399737
Type: Binding
Description: Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further incubation for 3 hrs by microplate reader based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4399737
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 349.43 | 3.33 | 3.33 |
| 340.38 | 2.68 | 2.68 |
| 395.44 | 3.19 | 3.19 |
| 362.39 | 3.22 | 3.22 |
| 327.34 | 2.46 | 2.46 |
| 369.42 | 3.38 | 3.38 |
| 279.30 | 0.96 | 0.96 |
| 363.37 | 2.62 | 2.62 |
| 312.33 | 2.07 | 2.07 |
| 384.43 | 3.25 | 3.25 |
| 363.37 | 2.62 | 2.62 |
| 355.39 | 3.08 | 3.08 |
| 357.37 | 2.47 | 2.47 |
| 379.42 | 2.79 | 2.79 |
| 403.44 | 4.13 | 4.13 |
| 416.48 | 3.76 | 3.76 |
| 377.40 | 3.61 | 3.61 |
| 402.40 | 2.09 | 2.09 |