Basic Information
ID: ALA4399996
Type: Binding
Description: Inhibition of recombinant human His-tagged TrkA kinase domain (441-796 residues) expressed in baculovirus expression system at 1 uM incubated with enzyme/ATP mixture for 20 mins by HTRF assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4399996
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 405.49 | 3.28 | 3.28 |
| 368.46 | 4.39 | 4.39 |
| 396.35 | 3.99 | 3.99 |
| 393.44 | 3.67 | 3.67 |
| 434.50 | 3.92 | 3.92 |
| 487.56 | 3.95 | 3.95 |
| 445.48 | 2.94 | 2.94 |
| 478.57 | 4.15 | 4.15 |
| 362.41 | 4.25 | 4.25 |
| 425.51 | 3.32 | 3.32 |
| 403.51 | 4.16 | 4.16 |
| 395.85 | 4.20 | 4.20 |
| 355.35 | 2.38 | 2.38 |
| 473.61 | 4.89 | 4.89 |
| 368.46 | 4.61 | 4.61 |
| 373.37 | 2.61 | 2.61 |
| 402.45 | 3.84 | 3.84 |
| 447.32 | 4.67 | 4.67 |
| 472.46 | 4.42 | 4.42 |
| 380.35 | 4.11 | 4.11 |
| 434.90 | 3.13 | 3.13 |
| 353.30 | 2.99 | 2.99 |
| 445.55 | 5.15 | 5.15 |
| 433.54 | 3.88 | 3.88 |
| 457.52 | 3.90 | 3.90 |
| 477.59 | 4.28 | 4.28 |
| 421.49 | 2.90 | 2.90 |
| 467.56 | 4.61 | 4.61 |
| 463.57 | 3.88 | 3.88 |
| 495.58 | 4.31 | 4.31 |