Basic Information
ID: ALA4399998
Type: Binding
Description: Inhibition of recombinant full length human TrkA transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4399998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.46 | 4.39 | 4.39 |
| 396.35 | 3.99 | 3.99 |
| 434.50 | 3.92 | 3.92 |
| 487.56 | 3.95 | 3.95 |
| 445.48 | 2.94 | 2.94 |
| 362.41 | 4.25 | 4.25 |
| 425.51 | 3.32 | 3.32 |
| 355.35 | 2.38 | 2.38 |
| 473.61 | 4.89 | 4.89 |
| 368.46 | 4.61 | 4.61 |
| 373.37 | 2.61 | 2.61 |
| 402.45 | 3.84 | 3.84 |
| 447.32 | 4.67 | 4.67 |
| 380.35 | 4.11 | 4.11 |
| 434.90 | 3.13 | 3.13 |
| 353.30 | 2.99 | 2.99 |
| 433.54 | 3.88 | 3.88 |
| 477.59 | 4.28 | 4.28 |
| 421.49 | 2.90 | 2.90 |
| 463.57 | 3.88 | 3.88 |