Basic Information
ID: ALA4400178
Type: Functional
Description: Antiinflammatory activity in C57BL/6 mouse primary peritoneal macrophages assessed as inhibition of LPS-induced TNFalpha production at 10 uM preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by sandwich ELISA
Format: BAO_0000219
Organism: Mus musculus
Strain: C57BL/6
Cell type: Peritoneal macrophage
Target: Peritoneal macrophage(ALA5314330)
Document: ALA4396951
Antiinflammatory activity in C57BL/6 mouse primary peritoneal macrophages assessed as inhibition of LPS-induced TNFalpha production at 10 uM preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by sandwich ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4400178
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 245.23 | 2.06 | 2.06 |
| 259.26 | 1.73 | 1.73 |
| 323.39 | 3.84 | 3.84 |
| 323.39 | 3.84 | 3.84 |
| 289.29 | 1.74 | 1.74 |
| 263.22 | 2.19 | 2.19 |
| 343.38 | 1.81 | 1.81 |
| 257.36 | 3.80 | 3.80 |
| 306.37 | 3.92 | 3.92 |
| 301.39 | 4.51 | 4.51 |
| 280.37 | 3.49 | 3.49 |
| 341.32 | 3.17 | 3.17 |
| 306.19 | 4.73 | 4.73 |
| 305.30 | 4.45 | 4.45 |
| 357.41 | 1.80 | 1.80 |
| 294.35 | 3.39 | 3.39 |
| 307.18 | 4.13 | 4.13 |
| 339.39 | 3.55 | 3.55 |
| 280.37 | 3.49 | 3.49 |
| 258.35 | 3.19 | 3.19 |
| 311.38 | 3.37 | 3.37 |
| 316.74 | 3.99 | 3.99 |
| 328.32 | 1.96 | 1.96 |
| 322.41 | 3.26 | 3.26 |
| 353.42 | 3.85 | 3.85 |
| 306.41 | 4.03 | 4.03 |
| 308.43 | 4.27 | 4.27 |
| 276.34 | 3.91 | 3.91 |
| 284.27 | 2.54 | 2.54 |
| 289.29 | 2.45 | 2.45 |
| 319.31 | 1.75 | 1.75 |
| 275.26 | 2.06 | 2.06 |
| 331.34 | 4.85 | 4.85 |
| 318.42 | 4.62 | 4.62 |
| 347.34 | 4.73 | 4.73 |
| 330.34 | 1.89 | 1.89 |
| 305.29 | 2.07 | 2.07 |
| 309.37 | 3.54 | 3.54 |