Basic Information
ID: ALA4400262
Type: Binding
Description: Inhibition of Plasmodium falciparum PKG expressed in Escherichia coli Rosetta 2 (DE3) pLysS preincubated for 30 mins using FAM-labeled PKAtide as substrate followed by addition of ATP at Km concentration and measured after 30 mins by microfluidic mobility shift assay
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4400262
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.44 | 3.28 | 3.28 |
| 403.47 | 2.93 | 2.93 |
| 403.47 | 2.93 | 2.93 |
| 468.61 | 3.88 | 3.88 |
| 392.44 | 3.12 | 3.12 |
| 482.64 | 4.23 | 4.23 |
| 385.48 | 3.87 | 3.87 |
| 405.48 | 3.54 | 3.54 |
| 391.45 | 3.15 | 3.15 |
| 405.48 | 3.61 | 3.61 |
| 336.32 | 2.45 | 2.45 |
| 282.35 | 1.74 | 1.74 |
| 362.41 | 3.24 | 3.24 |
| 403.47 | 3.30 | 3.30 |
| 350.47 | 3.55 | 3.55 |
| 362.41 | 3.24 | 3.24 |
| 308.39 | 2.31 | 2.31 |
| 417.49 | 3.69 | 3.69 |