Basic Information
ID: ALA4400317
Type: Functional
Description: Antiproliferative activity against human A549 cells harbouring EGFR G1202R mutant assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA4400317
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 558.15 | 6.36 | 6.36 |
| 480.91 | 4.24 | 4.24 |
| 524.03 | 5.85 | 5.85 |
| 538.05 | 6.28 | 6.28 |
| 610.12 | 6.17 | 6.17 |
| 495.97 | 5.21 | 5.21 |
| 481.94 | 4.82 | 4.82 |
| 510.00 | 5.65 | 5.65 |
| 524.03 | 6.04 | 6.04 |
| 569.07 | 4.43 | 4.43 |
| 553.07 | 5.19 | 5.19 |
| 525.01 | 4.36 | 4.36 |
| 452.90 | 4.32 | 4.32 |
| 466.93 | 4.93 | 4.93 |
| 497.94 | 3.79 | 3.79 |
| 528.04 | 5.16 | 5.16 |
| 555.04 | 3.73 | 3.73 |
| 466.93 | 4.71 | 4.71 |
| 526.99 | 3.95 | 3.95 |
| 522.99 | 5.61 | 5.61 |
| 510.00 | 5.60 | 5.60 |
| 540.02 | 5.01 | 5.01 |
| 611.10 | 5.67 | 5.67 |
| 492.97 | 5.63 | 5.63 |
| 582.06 | 5.39 | 5.39 |
| 481.94 | 4.50 | 4.50 |
| 625.13 | 6.11 | 6.11 |
| 538.01 | 5.22 | 5.22 |
| 511.97 | 4.45 | 4.45 |
| 554.01 | 4.91 | 4.91 |
| 481.00 | 6.33 | 6.33 |
| 480.96 | 5.10 | 5.10 |
| 537.02 | 6.00 | 6.00 |
| 582.06 | 5.39 | 5.39 |
| 481.94 | 4.87 | 4.87 |
| 466.97 | 5.94 | 5.94 |